This volume contains the original hieratic text, complete transcription into hieroglyphs, transliteration, English translation, philological apparatus and copiously illustrated medical commentaries for the 48 clinical cases of the Edwin Smith Papyrus, as well as extensive bibliographical resources, and a lucid introduction exploring the importance of the document, the history of previous scholarship, and distinctive aspects of the current edition. It offers an authoritative treatment of the Egyptian text, which clarifies the meaning of many passages from the papyrus and points the way to their correct medical interpretation. The Edwin Smith Papyrus is the first comprehensive trauma treatise in the history of medicine. Not only is the ESP the source of numerous anatomical and functional concepts of the nervous system, it is the basis for the development of modern objective clinical thinking, establishing the foundations of modern medicine more than a thousand years before Hippocrates. The volume features an impressive array of medical material that reveals the precise conditions described by the ancient physician and explores the Egyptian contribution to modern diagnostics, clinical practice, and methodology. This publication sets the standard in the presentation of ancient medical documents. It also includes the previously unpublished translation of the papyrus by Edwin Smith himself.